In Santana's only start against his team's crosstown rivals in 2009, the Yankees tattooed the left-hander for nine runs in three innings on their way to a 15-0 rout.
Santana will have a chance to redeem himself when he gets the start at Citi Field on Sunday night against fellow ace CC Sabathia in the Subway Series finale.
"It motivates me," Santana said. "I don't go crazy about it, but it's there. I want to pitch against them again. Just like the game in Philadelphia [this year], it's just one game."
With starters Jonathon Niese and John Maine on the disabled list, and Oliver Perez moved to the bullpen due to ineffectiveness, the Mets are counting on Santana and Mike Pelfrey to be their constants, a role Santana has filled his whole career.
"I wish I could pitch every day, but that's not the case -- I can't," Santana said. "We're going through a tough time with some injuries and stuff, but we have to keep playing the game. And every time we're out there, I'm trying to help."
-- Kyle Maistri