Before Friday's game against the Phillies, Manuel confirmed that Pat Misch, who is 11-4 with a 3.23 ERA for Triple-A Buffalo, will be called up to make the start.
Misch ascended to the Major League level last season, posting a 4.12 ERA in 59 innings, but he has spent all of 2010 down on the farm.
The 28-year-old lefty doesn't throw hard or strike out batters, which has helped keep him out of the Majors, according to Manuel.
"In all honesty, a lot of times, if you're left-handed and the left-handed hitters have a higher average against you than the right-handed hitters, and you're not a guy that let's say lights up the gun, you have to really be lights out with all the other parts of the game," Manuel said. "You're one of those guys that has to continue to prove that time in and time out, and I think that's what he's done -- he's proved that."